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1. Chaire en modélisation environnementale,
Trent University.
Mackay, D., Di Guardo A., Hickie, B., Webster, E. 1997. Environmental
Modelling: Progress and Prospects. SAR and QSAR in Environ.
Res. 6: 1-17.
Campfens, J. and Mackay D. 1997. Fugacity-Based Model of PCB
Bioaccumulation in Complex Aquatic Food Webs, Environ.
Sci. Technol. 31: 557-583.
Mackay D. Multimedia Mass Balance Models of Chemical Distribution
and Fate, Chapter 8 of Ecotoxicology edited by G. Schuurmann
and B. Markert and published by John Wiley, NY and Spektrum Press,
Berlin. pp. 237-257, 1997.
Mackay D, Paterson, S., Kicsi, G., Di Guardo, A., Cowan, C.E.
Assessing the Fate of New and Existing Chemicals: A Five Stage
Process. Environ. Toxicol. Chem. 15 No. 9 , 1618-1626,
1996.
Mackay D, Paterson, S., Di Guardo, A., Cowan, C.E. Evaluating
the Environmental Fate of a Variety of Types of Chemicals Using
the EQC Model, Environ. Toxicol. Chem. 15 No.9, 1627-1637,
1996.
Mackay D, Paterson, S., Kicsi, G., Cowan, C.E., Di Guardo, A.,
Kane, D.M. Assessment of Chemical Fate in the Environment Using
Evaluative, Regional and Local-Scale Models: Illustrative Application
to Chlorobenzene and Linear Alkylbenzene Sulfonates Environ.
Toxicol. Chem. 15 No.9, 1638-1648, 1996.
Mackay D. and Calcott, D. Partitioning and Physical Chemical
Properties of PAHs, Chapter 3 for Handbook of Environmental
Chemistry, PAHs and Related Compounds, edited by A.H. Neilson,
Published by Springer, Berlin. pp. 325-346. 1997.
Bentzen E, D.R.S. Lean, Taylor W.D., Mackay D. 1996. Role
of Food Web Structure on Lipid and Bioaccumulation of Organic
Contaminants by Lake Trout (Salvelinus namaycush). Can.
J. Fish. Aquat. 53: 2397-2407.
Wania, F., Mackay, D. 1996. Tracking the Distribution of Persistent
Organic Pollutants. Environ. Sci. Technol. 30: 390A-396A.
Boisset A., Mackay, D., Page, R. Environmental Events of 1995:
The Year in Review, Canadian Environmental Directory, 1995
Canadian Almanac and Director Publ. Co. Ltd., Toronto, pp.
1-8. 1995.
Mackay, D., Qiang, K. 1996. The Significance of Spills: How
Do Environmental Emergencies Affect Environmental Quality? Spill
Tech. Newsletter, Environment Canada, Ottawa. 21: 1-8.
Wania, F., Mackay, D. 1997. Global Distillation. Our
Planet: The United Nations Environment Programme Magazine for
Environmentally Sustainable Development. 8: 15-16.
Boisset, A., Mackay, D., Page R. 1997. 1996 Chronology of
Environmental Events. Canadian Environmental Directory
1997/98, Canadian Almanac and Directory Publ. Co. Ltd., Toronto.
Hung, H., Mackay, D. 1997. A Novel and Simple Model of the
Uptake of Organic Chemicals by Vegetation from Air and Soil. Chemosphere.
35: 959-977.
Mackay, D., Shiu, W.Y., Ma, K.C. 1997. Illustrated Handbook
of Physical Chemical Properties and Environmental Fate for Organic
Chemicals. Vol. 5 Pesticide Chemicals. Lewis Publishers/CRC
Press New York, N.Y.
Barrie, L., Macdonald, R., Bidleman, T., Diamond, M., Gregor,
D., Semkin, R., Strachan, W., Alaee, M., Backus, S., Bewers, M.,
Gobeil, C., Halsall, C, Hoff, J., Li, A., Lockhart, L., Mackay,
D., Muir, D., Pudykiewicz, J., Reimer, K., Smith, J., Stern G.,
Schroeder, W., Wagemann, R., Wania, F., Yunker, M. Chapter
2. Sources, Occurrence and Pathways. In: Jensen, J.,
Adare, K. and Shearer, R. (Eds) Canadian Arctic Contaminants
Assessment Report, Indian and Northern Affairs Canada, Ottawa
1997.
Wania, F., Pacyna, J.M., Mackay, D. 1997. Global Fate of Persistent
Organic Pollutants. Toxicol. Environ. Chem. 66: 81-89.
Mackay, D., Bentzen, E. 1997. The Role of the Atmosphere in
Great Lakes Contamination. Atmos. Environ. 31: 4043-4047.
Wania, F., Haugen, J.E., Lei, Y.D. Mackay, D. 1998. Temperature
Dependence of Atmospheric Concentrations of Semivolatile Organic
Compounds. Environ. Sci. Technol. 32: 1013-1021.
Hellou, J., Mackay, D., Banoub, J.H. 1998. Dietary and Aqueous
Exposure of Finfish to Organochlorine Compounds: A Case Study.
Environ. Contam. Toxicol. 34: 280-288.
Scott, S., Mackay, D., Webster E. 1998. Estimation of Spatially
Variable Atmospheric Concentrations Deduced from Regional Mass
Balance Models. Chemosphere 36: 2507-2522.
Thomas, G., Sweetman, A.J., Ockenden, W.A., Mackay, D. and Jones,
K.C. 1998. Air - Pasture Transfer of PCBs. Environ.
Sci. Technol. 32: 936-942.
Webster E., Mackay, D., Wania, F. 1998. Evaluating Environmental
Persistence. Environ. Toxicol. Chem. 17: 2148-2158.
Mackay, D., Webster, E. 1998. Linking Emissions to Prevailing
Concentrations - Exposure on a Local Scale. Environmetrics.
9: 541-553.
Vallack, H.W., Bakker, D.J., Brandt, I., Broström-Lundén,
E., Brouwer, A., Bull, K.R., Gough, C., Guardans, R., Holoubek,
I., Jansson, B., Koch, R., Kuylenstierna, J., Lecloux, A., Mackay,
D., McCutcheon, P., Mocarelli, P., Taalman, R.D.F. 1998. Controlling
persistent organic pollutants - what next? Environ. Toxicol.
Pharmacol. 6: 143-175.
Wania, F., Hoff, J.T., Jia, C.Q., Mackay, D. 1998. The effects
of snow and ice on the environmental behaviour of hydrophobic
organic chemicals. Environmental Pollution. 102: 25-41.
Hellou, J., Mackay, D., Banoub, J. 1999. Levels, persistence
and bioavailability of organic contaminants present in marine
harbor sediments impacted by raw sewage. Chemosphere. 38:
457-473.
Wania, F., Mackay, D., Hoff, J.T. 1999. The importance of snow
scavenging of PCB and PAH vapors. Environ. Sci. Technol.
33: 195-197.
Southwood, J., Muir, D.C.G., Mackay, D. 1999. Modelling agrochemical
dissipation in surface microlayers following aerial deposition.
Chemosphere. 38: 121-141.
MacLeod, M., Mackay, D. 1999. An assessment of the environmental
fate and exposure of benzene and the chlorobenzenes in Canada.
Chemosphere 38: 1777-1796.
Mackay, D., Shiu, W.Y., Ma, K.C. Physical-Chemical Properties
and Environmental Fate and Degradation Handbook. CRCnetBASE
1999, Chapman & Hall CRCnetBASE, CRC Press LLC., Boca Raton,
FL. (CD-ROM.)
Wania, F., Mackay, D., Li, Y.F., Bidleman, T.F., Strand, A. 1999.
Global chemical fate of a-hexachlorocyclohexane. 1. Modification
and evaluation of a global distribution model. Environ.
Toxicol. Chem. 18: 1390-1399.
Wania, F., Mackay, D. 1999. Global chemical fate of a-hexachlorocyclohexane.
2. Use of a global distribution model for mass balancing, source
apportionment, and trend prediction. Environ. Toxicol.
Chem. 18:1400-1407.
Seth, R., Mackay, D., Muncke, J. 1999. Estimating of Organic
Carbon Partition Coefficient and Its Variability for Hydrophobic
Chemicals. Environ. Sci. Technol. 33: 2390-2394.
Boethling, R.S., Calamari, D., Cowan-Ellsberry, C., Eisenreich,
S., Franklin, J., Grady Jr., C.P.L., Graham, D.G., Hansen, B.,
Howard, P.H., Jones, K.C., Kannan, K., Kle_ka, G.M., Larson, R.J.,
Macdonald, R.W., Mackay, D., McKone, T., Muir, D., Parkerton,
T., Thibodeaux, L., van de Meent, D., Wallington, T., Zetzsch,
C. Evaluation of Persistence and Long-Range Transport
of Organic Chemicals in the Environment: Summary of a SETAC Pellston
Workshop. Kle_ka, G.M. and Mackay, D. (Eds.) SETAC Press.
1999.
Mackay, D., Shiu, W.Y., Ma, K.C. Physical-Chemical Properties
and Environmental Fate and Degradation Handbook. CRCnetBASE
1999. Chapman & Hall CRCnetBASE, CRC Press LLC., Boca Raton,
FL. (CD-ROM.) Go to 2000 edition
Hellou, J., Mackay, D., Banoub, J. 1999. Levels, persistence
and bioavailability of organic contaminants present in marine
harbor sediments impacted by raw sewage. Chemosphere. 38:
457-473.
Wania, F., Mackay, D., Hoff, J.T. 1999. The importance of
snow scavenging of PCB and PAH vapors. Environ. Sci. Technol.
33: 195-197.
Bahadur, N., Shiu, W.-Y., Boocock, D., Mackay, D. 1999. Tricaprylin-Water
Partition Coefficients and Their Temperature Dependence for Selected
Chlorobenzenes. J. Chem. Eng. Data. 44: 40-43.
Cole, J.G., Mackay, D., Jones, K.C., Alcock, R.E. 1999. Interpreting,
Correlating, and Prediciting the Multimedia Concentrations of
PCDD/Fs in the United Kingdom. Environ. Sci. Technol. 33:
399-405.
Webster, E., Mackay, D., Qiang, K. 1999. Equilibrium Lipid
Partitioning Concentrations as a Multi-media Synoptic Indicator
of Contaminant Levels and Trends in Aquatic Ecosystems. J.
Great Lakes Res. 25: 318-329. View Brief Report
Reed, M., Johansen, Ø., Brandvik, P.J., Daling, P., Lewis,
A., Fiocco, R., Mackay, D., Prentki, R. 1999. Oil Spill Modeling
towards the Close of the 20th Century: Overview of the State of
the Art. Spill Science and Technology. 5: 3-16.
Seth, R., Mackay, D. 1999. Do Toxic Chemical Spills Contribute
Significantly to Human and Environmental Exposure in Canada? Spill
Technology Newsletter. 24: 1-8.
Wania, F., Mackay, D. 1999. The Evolution of Mass Balance
Models of Persistent Organic Pollutant Fate in the Environment.
Environ. Pollution. 100: 223-240.
Mackay, D., Seth, R. "The Role of Mass Balance Modelling
in Impact Assessment and Pollution Prevention" In Tools
and Methods for Pollution Prevention. Sikdar, S.K., Diweker,
U. Eds. Kluwer Academic Publishers. 1999. pp 157-179.
Cousins, I.T., Mackay, D., Jones, K.C. 1999. Measuring and
modelling the vertical distribution of semi-volatile organic compounds
in soils. II: Model development. Chemosphere. 39: 2519-2534.
Hickie, B.E., Mackay, D., de Koning, J. 1999. A lifetime pharmacokinetic
model for hydrophobic contaminants in marine mammals. Environ.
Toxicol. Chem. 18: 2622-2633.
Mackay, D. "Chemical Contaminants in Ontario: an Evolving
Enivornmental Issue of the 21st Century" In Emerging
Environmental Issues in Ontario. Munn, R.E., Ed. Institute
for Environmental Studies, University of Toronto, M5S 3E8, Report
of a Workshop. November 19, 1999. pp 41-44.
Bentzen, E., Mackay, D., Hickie, B.E., Lean, D.R.S. 1999.Temporal
trends of persistent organic pollutants in Lake Ontario compared
between species and between data sources. Environmental
Reviews. 7: 203-223.
Thompson, S., Mackay, D., MacLeod, M. 1999. A Modelling Strategy
for Planning Virtual Elimination of Persistent Toxic Chemicals
from the Great Lakes: An Illustration of Four Contaminants in
Lake Ontario. J. Great Lakes Res. 25: 814 - 827. Abstract
Mackay, D., Shiu, W.Y., Ma, K.C. Physical-Chemical Properties
and Environmental Fate and Degradation Handbook. CRCnetBASE
2000, Chapman & Hall CRCnetBASE, CRC Press LLC., Boca Raton,
FL. (CD-ROM.) CRC Press catalogue entry
Cole, J.G., Mackay, D. 2000. Correlation of Environmental
Partitioning Properties of Organic Compounds: The Three Solubilities
Approach. Environ. Toxicol. Chem. 19: 265-270.
Beyer, A., Mackay, D., Matthies, M., Wania, F., Webster, E. 2000.
Assessing Long-range Transport Potential of Persistent Organic
Pollutants. Environ. Sci. Tech. 34: 699-703.
Gouin T., Mackay D., Webster E., Wania F. 2000. Screening
Chemicals for Persistence in the Environment. Environ.
Sci. Technol. (Published Feb. 2, 2000.)
Sous presse
Hickie, B.E., Kingsley, M.C.S., Hodson, P.V., Muir, D.C.G., Beland,
P., Mackay, D. 2000. A modelling-based perspective on the past,
present and future PCB contamination of the St. Lawrence beluga
whale population (Delphinapterus leucas). Can J Fish Aquat.
Sci. (Accepted March 1999)
Mackay, D., Hickie, B. 2000. Mass Balance Model of Sources,
Transport, and Fate of PAHs in Lac Saint Louis, Quebec. Chemosphere.
(Accepted June 1999)
Cousins, I.T., Mackay, D. 2000. Correlating the Physical Chemical
Properties of Phthalate Esters using the "Three Solubilities
Approach". Chemosphere. (Accepted October 1999)
Woodfine D.G., Seth R., Mackay D., Havas M. 2000. Simulating
the Response of Metal Contaminated Lakes to Reductions in Atmospheric
Loading Using a Modified QWASI Model. Chemosphere. (Accepted
November 1999.)
Mackay, D., Webster, E., Beyer, A., Matthies, M., Wania, F. "Defining
the Bioaccumulation, Persistence, and Transport Attributes of
Priority Chemicals" In American Chemical Society Symposium
Series on Persistent Organic Pollutants. R. Lipnick, Ed. (In
press.)
2. Évaluation systématique des substances
éstrogéniques.
Zacharewski, T.R., McCallum, G.P., Stegeman, J.J. and Bend, J.R.
(1996) Hepatic cytochrome P450 1A as a biomarker for hydrocarbon
and oxidant pollutants in fish: relevance of identification of
specific mechanism(s) of induction and potential effects on homeostasis.
In Environmental Toxicology and Risk Assessment: Transboundary
Issues in Pollution-Air, Surface and Groundwater (T. W. La
Point, F. T. Price, & E. E. Little, Eds.), American Society
for Testing and Materials, Philadelphia. p. l65 187.
Safe, S. and Zacharewski, T. (1997) Organochlorine exposure
and breast cancer. In Etiology of Breast Cancer. Progress
in Clinical and Biological Research, Vol 396 (C.M. Aldaz,
M.N. Gould, J. McLachlan, T.F. Slaga, Eds.). p. 133-146.
McCallum, C,.P. and Zacharewski, T. (1997) Molecular Toxicology:
Applications of recombinant DNA technology. In Encyclopedia
of Toxicology (P. Wexler, Ed). Vol. 2, p 335-342.
Zacharewski, T. and Safe, S. (1997) Antiestrogenic activity
of TCDD and related compounds. In Modulation of Endocrine
Systems by Xenobiotics (K. Korach, Ed.). p 431- 448.
Van Der Kraak, G., Zacharewski. T., Janz, D. and Sanders, B.
(1998) Comparative endocrinology and mechanisms of endocrine
modulation in fish and wildlife. In Principle and Processes
for Evaluating Endocrine Disruption in Wildlife (R.J. Kendall,
R.L. Dickerson, W.A. Suk, and J.P. Giesy, Eds.). p. 97-119.
Clemons, J.H. and Zacharewski, T. (1997) Reporter genes in
toxicology. In Molecular Biology Approaches to Toxicology
(A. Puga and K.B. Wallace, Eds.). In press.
Zacharewski, T., Berhane, K., Cillesby, B. and Burnison, B.K.
(1995) Evidence for the presence of estrogen receptor and Ah
receptor ligands in pulp and paper mill black liquor. Environmental
Science and Technology, 29, 2140-2146.
Ruh, M.F., Zacharewski, T., Connor, K., Howell, J., Chen, 1.
and Safe, S. (1995) Naringenin: a weakly estrogenic bioflavonoid
which exhibits antiestrogenic activity. Biochemical Pharmacology,
50, 1485-1493.
Connor, K., Howell, J., Chen, I., Liu, H., Berhane, K., Sciarretta,
C., Safe, S. and Zacharewski, T. (1996) Failure of chloro-S-triazine-derived
compounds to induce estrogen receptor-mediated responses in vivo
and in vitro. Fundamental and Applied Toxicology, 30,
93-101.
Moore, M., Mustain, M., DaWel, K., Chen, I., Safe, S., Zacharewski,
T., Gillesby, B., Joyeux, A. and Balaguer, P. (1997) Antiestrogenic
activity of hydroxylated polychlorinated biphenyl congeners identified
in human serum. Toxicology and Applied Pharmacology,
142, 160-168, 1997.
Zacharewski, T. (1997) In vitro bioassays for assessing estrogenic
substances. Environmental Science and Technology, 31,
613-623.
Gillesby, B., Stanostefano, M., Wu, Z. F., Safe, S., and Zacharewtiki,
T. (1997) Identification of an inhibitory dioxin-like response
elernent (IDRE) required for TCDD- mediated suppression of pS2
expression. Biochemistry, 36, 6080-6089.
Connor, K., Rarnarnoorthy, K., Moore, M., Mustain, M., Chen,
I., Safe, S. Zacharewski, T., Gillesby, B., Joyeux, A. and Balaguer,
P. (1997) Hydroxylated polychlorinated biphenyls (PCBS) as
estrogens and antiestrogens: structure-activity relationships.
Toxicology and Applied Pharmacology, 145,111 123.
Meek, M.D., Clemons, J.H., Wu, Z.F. and Zacharewski, T. (1997)
Examination of the estrogenic activities of eight coriimercial
phthalate esters. Fundamental and Applied Toxicology.
Submitted
Fielden, M.R., Chen, I., Chittim, B., Safe, S. and Zacharewski,
T. Examination of the estrogenicity of 2,4,6,2',6'-pentacl-dorobiphenyl
(PCB104) and its hydroxylated 2,4,6,2',6'-pentachloro-4-biphenylol
(HO-PCB104) and chlorinated, 2,4,6,2',4',6'- hexachlorobiphenyl
(PCB155) drivatives. Environmental Health Perspectives.
In press
Gillesby, B.E. and Zacharewski, T. (1998) Endocrine disrupters:
mechanisms of action and strategies for identification and assessment.
Environmental Toxicology and Chemistry. 17, 3-14.
Berhane, K. and Zacharewski, T. Bacterial expression of the
aryl hydrocarbon receptor (AhR) and its dimerization partner,
the aryl hydrocarbon receptor nuclear translocator protein (ARNT).
Partially purified A-hR and ARNT are sufficient for binding to
a dioxin response element in vitro. In preparation
Clemons, J.H., Marvin, C.R., Wu, Z.F., McCarry, B.E., Legzdins,
A.E., Bryant, D.W. and Zacharewski, T.R. (1998). Identification
of estrogen- and dioxin-like activities in urban air particulate
material using recombinant receptor/reporter gene bioassays.
Environmental Science and Technology, 32, 1853-1860
Desaulniers, D., Leingartner, K., Zacharewski, T. and Foster,
W.G. Optimization of an MCF7-E3 cell proliferation assay and
effects of environmental pollutants and industrial chemicals.
Toxicology In vitro. In press.
Balaguer, P., Joyeux, A. M., Denison, M.S., Vincent, R., Cillesby,
B. and Zacharewski, T. (1996) Assessing the estrogenic and
dioxin-like activities of chemicals and complex mixtures using
in vitro recombinant receptor/reporter gene assays. Canadian
Journal of Physiology and Pharmacology, 74, 216-222.
Zacharewski, T. (1997) Endocrine disruption: Strategies for
identification and assessment. SGOMSEC 13 - Altemative Toxicological
Testing Methods. Environmental Health Perspectives,
in press
Tillit, D., Kramer, V., Purdy, R. and Zacharewski, T. (1997)
In vitro screening methods for endocrine disruptors in wildlife.
in preparation.
Zacharewski, T., Campbell P.M., Routledge, E., Cooper, R., Huet,
M.-C., Kirne, D. and Wenzel, A. (1997) Current approaches for
the use of in vitro tests in identifying the hazards of endocrine
modulating chemicals to wildlife. In SETAC-Europe/OECD/EC
Expert Workshop on Endocrine Modulators and Wildlife: Assessment
and testing (EMWAT) (L. Tattersfield, P. Matthiessen, P. Campbell,
N, Grandy, R. Lange, Eds.), SETAC Europe Publication, Brussels.
p. 41-58.
Gray, L.E., Kelce, W.R., Wiese, T., Tyl, R., Gaido, K., Cook,
J., Klinefelter, G., Desaulniers, D., Wilson, E., Zacharewski,
T., Waller, C., Foster, P., Laskey, J., Reel, J., Giesy, J., Breslin,
W., Cooper, R., Di Giulio, R., Welshons, W., Miller, R., Safe,
S., McLachlan, J., McMaster, S., Colborn, T. (1997) Endocrine
Screening Methods Workshop Report: Detection of Estrogenic and
Androgenic Hormonal and Antihormonal Activity for Chemicals that
act via Receptor or Steroidogenic Enzyme Mechanisms. Reproductive
Toxicology, 11, 719-750.
3. Toxicologie du système de reproduction
et du système endocrinien chez le poisson.
Hewitt, L.M., Scott, I.M., Munkittrick, K.R., Van Der Kraak,
G.J., Solomon, K.R., and Servos, M.R., 1996. Development of
TIEs for complex mixtures using physiological responses in fish.
In: Environmental Toxicology and Risk Assessment: Biomarkers
and Risk Assessment Fifth Volume. ASTM STP 1306. (D.A. Bengston
and D.S. Henshel, eds.). American Society for Testing and Materials,
Philadelphia, pp. 37-52.
Hewitt, L.M., L. Tremblay, G.J. Van der Kraak, K.R. Solomon and
M.R. Servos, 1998. Identification of the lampricide 3-trifluoromethyl-4-nitrophenol
as an agonist for the rainbow trout estrogen receptor. Environ.
Toxicol. Chem. 17:425-432.
Janz, D.M. and G. Van Der Kraak, 1997. Suppression of apoptosis
by gonadotropin, 17B-estradiol, and epidermal growth factor in
rainbow trout preovulatory ovarian follicles. Gen. comp. Endocrinol.
105:186-193.
Janz, D.M., M.E. McMaster, K.R. Munkittrick, and G. Van Der Kraak,
1997. Elevated ovarian follicular apoptosis and heat shock
protein-70 expression in white sucker exposed to bleached kraft
pulp mill effluent. Toxicol. Appl. Pharmacol. 147:391-398.
Tremblay, L. and G. Van der Kraak, 1998. Use of a series of
homologous in vitro and in vivo assays to evaluate the endocrine
modulating actions of beta-sitosterol in rainbow trout. Aquat.
Toxicol. 43:149-162.
Tremblay, L. and G. Van der Kraak, 1999. Comparision between
the effects of the phytosterol B-sitosterol and pulp and paper
mill effluents on sexually immature rainbow trout. Environ.
Toxicol. Chem., in press.
4. Évaluation du risque environnemental
associé aux hydrocarbures aromatiques halogénés.
(95-02)
Morrison, H.A., D.M. Whittle, C.D. Metcalfe and A.J. Niimi, 1999.
Verification and use of a food web bioaccumulation model for
the prediction of PCB, dioxin and furan congener concentrations
in Lake Ontario biota. Can. J. Fish. Aquat. Sci. 56
(In press).
Morrison, H.A., C.D. Metcalfe, D. Mackay, A.J. Niimi and D.M.
Whittle. Assessing the risk to Lake Ontario anglers consuming
sport fish contaminated with halogenated aromatic hydrocarbons.
Environ. Health Persp. (Accepted).
5. Métabolites des BPC dans le plasma
et le lait humains. (95-04)
Sandau C.D., Norstrom R.J. Comparison of methylation methods
for the determination of hydroxy-PCBs and preliminary results
for polar bear blood plasma. Organohalogen Compounds
29:412-417 (1996).
Sandau C.D., Ayotte, P., Dewailly, E., Bergman, A., Klasson-Wehler,
E., Norstrom R.J. Analysis of hydroxylated metabolites of PCBs
(OH-PCBs) in whole blood from Canadian Inuit. Organohalogen
Compounds 38:29-32 (1998)
C.D. Sandau, R.J. Norstrom. Analysis of hydroxylated metabolites
of PCBs (OH-PCBs) in polar bear plasma and human whole blood.
EnviroAnalysis'98, Proceedings of the second biennial international
conference on chemical measurement and monitoring of the environment.
405-410 (1998)
Sandau, C.D., P. Ayotte, E. Dewailly, J. Duffe and R.J. Norstrom.
2000. Analysis of hydroxylated metabolites of PCBs (OH-PCBs)
and other chlorinated phenolic compounds in whole blood from Canadian
Inuit. Environ. Health Persp. (in press)
Sandau, C.D., I.T.M. Meerts, R.J. Letcher, A.J. McAlees, B. Chittim,
A. Brouwer and R.J. Norstrom. 2000. Identification of 4-hydroxy-heptachlorostyrene
in polar bear plasma and its binding affinity to transthyretin:
a metabolite of octachlorostyrene? Submitted to ES&T
Sandau, C.D., P. Ayotte, E. Dewailly, J. Duffe, R.J. Norstrom.
PCP and hydroxylated metabolites of PCBs in umbilical cord
plasma from three different regions of Quebec - Nunavik, Gulf
of the St. Lawrence and Quebec City. (In prep.)
6. Synthèse et toxicologie aquatique
de chloroalcanes individuels de différentes origines (95-05)
Fisk, A.T., G.T. Tomy, and D.C.G. Muir. 1999. The toxicity
of C10, C11-, C12- and C14- polychlorinated alkanes to Japanese
medaka (Oryzias latipes) embryos. Environ. Toxicol.
Chem. 18(12): In press.
Cooley, M., Fisk, A.T., Wiens, S., Tomy, G.T. and D.C.G. Muir.
2000. Examination of the behavior and the liver, kidney and
thyroid histology of juvenile rainbow trout (Oncorhynchus mykiss)
exposed to high dietary concentrations of C10-, C11-, C12- and
C14-polychlorinated n-alkanes. In preparation. Aquatic
Toxiol.
Fisk, A.T., Tomy, G.T., Cymbalisty, C.D. and D.C.G. Muir. 1999.
Dietary accumulation, depuration and biodegradation of short
(C10), medium (C14) and long (C18) carbon chain polychlorinated
alkanes by juvenile rainbow trout (Oncorhynchus mykiss):
Relationships with carbon chain length and chlorine content.
In preparation. Environ. Toxicol. Chem. Submitted June,1999.
7. Tératogénicité relative
des congénères du toxaphène prévalants dans
l'environnement.
Stalzer, A. Chan, H.M. (1999) The relative estrogenic activity
of technical toxaphene mixture and two individual congeners.
Toxicology. In press.
Chan, H.M., Zhu, J., Yeboah, F. (1998) Determination of toxaphene
in biological samples using high resolution GC coupled with ion
trap MS/MS. Chemosphere, 36:2135-2148.
Calciu, C., Chan, H.M. Kubow, S. (1997) Toxaphene congeners
differ from toxaphene mixtures in their dysmorphogenic effects
on cultured rat embryos. Toxicology, 153-162.
8. Étude de l'occurrence, de la distribution
et de l'origine biogénétique des composés chlorés
organiques, y compris les dioxines et les furanes polychlorés,
dans les tourbières.
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