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1. Chaire en modélisation environnementale, Trent University.

    Mackay, D., Di Guardo A., Hickie, B., Webster, E. 1997. Environmental Modelling: Progress and Prospects. SAR and QSAR in Environ. Res. 6: 1-17.

    Campfens, J. and Mackay D. 1997. Fugacity-Based Model of PCB Bioaccumulation in Complex Aquatic Food Webs, Environ. Sci. Technol. 31: 557-583.

    Mackay D. Multimedia Mass Balance Models of Chemical Distribution and Fate, Chapter 8 of Ecotoxicology edited by G. Schuurmann and B. Markert and published by John Wiley, NY and Spektrum Press, Berlin. pp. 237-257, 1997.

    Mackay D, Paterson, S., Kicsi, G., Di Guardo, A., Cowan, C.E. Assessing the Fate of New and Existing Chemicals: A Five Stage Process. Environ. Toxicol. Chem. 15 No. 9 , 1618-1626, 1996.

    Mackay D, Paterson, S., Di Guardo, A., Cowan, C.E. Evaluating the Environmental Fate of a Variety of Types of Chemicals Using the EQC Model, Environ. Toxicol. Chem. 15 No.9, 1627-1637, 1996.

    Mackay D, Paterson, S., Kicsi, G., Cowan, C.E., Di Guardo, A., Kane, D.M. Assessment of Chemical Fate in the Environment Using Evaluative, Regional and Local-Scale Models: Illustrative Application to Chlorobenzene and Linear Alkylbenzene Sulfonates Environ. Toxicol. Chem. 15 No.9, 1638-1648, 1996.

    Mackay D. and Calcott, D. Partitioning and Physical Chemical Properties of PAHs, Chapter 3 for Handbook of Environmental Chemistry, PAHs and Related Compounds, edited by A.H. Neilson, Published by Springer, Berlin. pp. 325-346. 1997.

    Bentzen E, D.R.S. Lean, Taylor W.D., Mackay D. 1996. Role of Food Web Structure on Lipid and Bioaccumulation of Organic Contaminants by Lake Trout (Salvelinus namaycush). Can. J. Fish. Aquat. 53: 2397-2407.

    Wania, F., Mackay, D. 1996. Tracking the Distribution of Persistent Organic Pollutants. Environ. Sci. Technol. 30: 390A-396A.

    Boisset A., Mackay, D., Page, R. Environmental Events of 1995: The Year in Review, Canadian Environmental Directory, 1995 Canadian Almanac and Director Publ. Co. Ltd., Toronto, pp. 1-8. 1995.

    Mackay, D., Qiang, K. 1996. The Significance of Spills: How Do Environmental Emergencies Affect Environmental Quality? Spill Tech. Newsletter, Environment Canada, Ottawa. 21: 1-8.

    Wania, F., Mackay, D. 1997. Global Distillation. Our Planet: The United Nations Environment Programme Magazine for Environmentally Sustainable Development. 8: 15-16.

    Boisset, A., Mackay, D., Page R. 1997. 1996 Chronology of Environmental Events. Canadian Environmental Directory 1997/98, Canadian Almanac and Directory Publ. Co. Ltd., Toronto.

    Hung, H., Mackay, D. 1997. A Novel and Simple Model of the Uptake of Organic Chemicals by Vegetation from Air and Soil. Chemosphere. 35: 959-977.

    Mackay, D., Shiu, W.Y., Ma, K.C. 1997. Illustrated Handbook of Physical Chemical Properties and Environmental Fate for Organic Chemicals. Vol. 5 Pesticide Chemicals. Lewis Publishers/CRC Press New York, N.Y.

    Barrie, L., Macdonald, R., Bidleman, T., Diamond, M., Gregor, D., Semkin, R., Strachan, W., Alaee, M., Backus, S., Bewers, M., Gobeil, C., Halsall, C, Hoff, J., Li, A., Lockhart, L., Mackay, D., Muir, D., Pudykiewicz, J., Reimer, K., Smith, J., Stern G., Schroeder, W., Wagemann, R., Wania, F., Yunker, M. “Chapter 2. Sources, Occurrence and Pathways”. In: Jensen, J., Adare, K. and Shearer, R. (Eds) Canadian Arctic Contaminants Assessment Report, Indian and Northern Affairs Canada, Ottawa 1997.

    Wania, F., Pacyna, J.M., Mackay, D. 1997. Global Fate of Persistent Organic Pollutants. Toxicol. Environ. Chem. 66: 81-89.

    Mackay, D., Bentzen, E. 1997. The Role of the Atmosphere in Great Lakes Contamination. Atmos. Environ. 31: 4043-4047.

    Wania, F., Haugen, J.E., Lei, Y.D. Mackay, D. 1998. Temperature Dependence of Atmospheric Concentrations of Semivolatile Organic Compounds. Environ. Sci. Technol. 32: 1013-1021.

    Hellou, J., Mackay, D., Banoub, J.H. 1998. Dietary and Aqueous Exposure of Finfish to Organochlorine Compounds: A Case Study. Environ. Contam. Toxicol. 34: 280-288.

    Scott, S., Mackay, D., Webster E. 1998. Estimation of Spatially Variable Atmospheric Concentrations Deduced from Regional Mass Balance Models. Chemosphere 36: 2507-2522.

    Thomas, G., Sweetman, A.J., Ockenden, W.A., Mackay, D. and Jones, K.C. 1998. Air - Pasture Transfer of PCBs. Environ. Sci. Technol. 32: 936-942.

    Webster E., Mackay, D., Wania, F. 1998. Evaluating Environmental Persistence. Environ. Toxicol. Chem. 17: 2148-2158.

    Mackay, D., Webster, E. 1998. Linking Emissions to Prevailing Concentrations - Exposure on a Local Scale. Environmetrics. 9: 541-553.

    Vallack, H.W., Bakker, D.J., Brandt, I., Broström-Lundén, E., Brouwer, A., Bull, K.R., Gough, C., Guardans, R., Holoubek, I., Jansson, B., Koch, R., Kuylenstierna, J., Lecloux, A., Mackay, D., McCutcheon, P., Mocarelli, P., Taalman, R.D.F. 1998. Controlling persistent organic pollutants - what next? Environ. Toxicol. Pharmacol. 6: 143-175.

    Wania, F., Hoff, J.T., Jia, C.Q., Mackay, D. 1998. The effects of snow and ice on the environmental behaviour of hydrophobic organic chemicals. Environmental Pollution. 102: 25-41.

    Hellou, J., Mackay, D., Banoub, J. 1999. Levels, persistence and bioavailability of organic contaminants present in marine harbor sediments impacted by raw sewage. Chemosphere. 38: 457-473.

    Wania, F., Mackay, D., Hoff, J.T. 1999. The importance of snow scavenging of PCB and PAH vapors. Environ. Sci. Technol. 33: 195-197.

    Southwood, J., Muir, D.C.G., Mackay, D. 1999. Modelling agrochemical dissipation in surface microlayers following aerial deposition. Chemosphere. 38: 121-141.

    MacLeod, M., Mackay, D. 1999. An assessment of the environmental fate and exposure of benzene and the chlorobenzenes in Canada. Chemosphere 38: 1777-1796.

    Mackay, D., Shiu, W.Y., Ma, K.C. Physical-Chemical Properties and Environmental Fate and Degradation Handbook. CRCnetBASE 1999, Chapman & Hall CRCnetBASE, CRC Press LLC., Boca Raton, FL. (CD-ROM.)

    Wania, F., Mackay, D., Li, Y.F., Bidleman, T.F., Strand, A. 1999. Global chemical fate of a-hexachlorocyclohexane. 1. Modification and evaluation of a global distribution model. Environ. Toxicol. Chem. 18: 1390-1399.

    Wania, F., Mackay, D. 1999. Global chemical fate of a-hexachlorocyclohexane. 2. Use of a global distribution model for mass balancing, source apportionment, and trend prediction. Environ. Toxicol. Chem. 18:1400-1407.

    Seth, R., Mackay, D., Muncke, J. 1999. Estimating of Organic Carbon Partition Coefficient and Its Variability for Hydrophobic Chemicals. Environ. Sci. Technol. 33: 2390-2394.

    Boethling, R.S., Calamari, D., Cowan-Ellsberry, C., Eisenreich, S., Franklin, J., Grady Jr., C.P.L., Graham, D.G., Hansen, B., Howard, P.H., Jones, K.C., Kannan, K., Kle_ka, G.M., Larson, R.J., Macdonald, R.W., Mackay, D., McKone, T., Muir, D., Parkerton, T., Thibodeaux, L., van de Meent, D., Wallington, T., Zetzsch, C. “Evaluation of Persistence and Long-Range Transport of Organic Chemicals in the Environment: Summary of a SETAC Pellston Workshop”. Kle_ka, G.M. and Mackay, D. (Eds.) SETAC Press. 1999.

    Mackay, D., Shiu, W.Y., Ma, K.C. Physical-Chemical Properties and Environmental Fate and Degradation Handbook. CRCnetBASE 1999. Chapman & Hall CRCnetBASE, CRC Press LLC., Boca Raton, FL. (CD-ROM.) Go to 2000 edition

    Hellou, J., Mackay, D., Banoub, J. 1999. Levels, persistence and bioavailability of organic contaminants present in marine harbor sediments impacted by raw sewage. Chemosphere. 38: 457-473.

    Wania, F., Mackay, D., Hoff, J.T. 1999. The importance of snow scavenging of PCB and PAH vapors. Environ. Sci. Technol. 33: 195-197.

    Bahadur, N., Shiu, W.-Y., Boocock, D., Mackay, D. 1999. Tricaprylin-Water Partition Coefficients and Their Temperature Dependence for Selected Chlorobenzenes. J. Chem. Eng. Data. 44: 40-43.

    Cole, J.G., Mackay, D., Jones, K.C., Alcock, R.E. 1999. Interpreting, Correlating, and Prediciting the Multimedia Concentrations of PCDD/Fs in the United Kingdom. Environ. Sci. Technol. 33: 399-405.

    Webster, E., Mackay, D., Qiang, K. 1999. Equilibrium Lipid Partitioning Concentrations as a Multi-media Synoptic Indicator of Contaminant Levels and Trends in Aquatic Ecosystems. J. Great Lakes Res. 25: 318-329. View Brief Report

    Reed, M., Johansen, Ø., Brandvik, P.J., Daling, P., Lewis, A., Fiocco, R., Mackay, D., Prentki, R. 1999. Oil Spill Modeling towards the Close of the 20th Century: Overview of the State of the Art. Spill Science and Technology. 5: 3-16.

    Seth, R., Mackay, D. 1999. Do Toxic Chemical Spills Contribute Significantly to Human and Environmental Exposure in Canada? Spill Technology Newsletter. 24: 1-8.

    Wania, F., Mackay, D. 1999. The Evolution of Mass Balance Models of Persistent Organic Pollutant Fate in the Environment. Environ. Pollution. 100: 223-240.

    Mackay, D., Seth, R. "The Role of Mass Balance Modelling in Impact Assessment and Pollution Prevention" In Tools and Methods for Pollution Prevention. Sikdar, S.K., Diweker, U. Eds. Kluwer Academic Publishers. 1999. pp 157-179.

    Cousins, I.T., Mackay, D., Jones, K.C. 1999. Measuring and modelling the vertical distribution of semi-volatile organic compounds in soils. II: Model development. Chemosphere. 39: 2519-2534.

    Hickie, B.E., Mackay, D., de Koning, J. 1999. A lifetime pharmacokinetic model for hydrophobic contaminants in marine mammals. Environ. Toxicol. Chem. 18: 2622-2633.

    Mackay, D. "Chemical Contaminants in Ontario: an Evolving Enivornmental Issue of the 21st Century" In Emerging Environmental Issues in Ontario. Munn, R.E., Ed. Institute for Environmental Studies, University of Toronto, M5S 3E8, Report of a Workshop. November 19, 1999. pp 41-44.

    Bentzen, E., Mackay, D., Hickie, B.E., Lean, D.R.S. 1999.Temporal trends of persistent organic pollutants in Lake Ontario compared between species and between data sources. Environmental Reviews. 7: 203-223.

    Thompson, S., Mackay, D., MacLeod, M. 1999. A Modelling Strategy for Planning Virtual Elimination of Persistent Toxic Chemicals from the Great Lakes: An Illustration of Four Contaminants in Lake Ontario. J. Great Lakes Res. 25: 814 - 827. Abstract

    Mackay, D., Shiu, W.Y., Ma, K.C. Physical-Chemical Properties and Environmental Fate and Degradation Handbook. CRCnetBASE 2000, Chapman & Hall CRCnetBASE, CRC Press LLC., Boca Raton, FL. (CD-ROM.) CRC Press catalogue entry

    Cole, J.G., Mackay, D. 2000. Correlation of Environmental Partitioning Properties of Organic Compounds: The Three Solubilities Approach. Environ. Toxicol. Chem. 19: 265-270.

    Beyer, A., Mackay, D., Matthies, M., Wania, F., Webster, E. 2000. Assessing Long-range Transport Potential of Persistent Organic Pollutants. Environ. Sci. Tech. 34: 699-703.

    Gouin T., Mackay D., Webster E., Wania F. 2000. Screening Chemicals for Persistence in the Environment. Environ. Sci. Technol. (Published Feb. 2, 2000.)

    Sous presse

    Hickie, B.E., Kingsley, M.C.S., Hodson, P.V., Muir, D.C.G., Beland, P., Mackay, D. 2000. A modelling-based perspective on the past, present and future PCB contamination of the St. Lawrence beluga whale population (Delphinapterus leucas). Can J Fish Aquat. Sci. (Accepted March 1999)

    Mackay, D., Hickie, B. 2000. Mass Balance Model of Sources, Transport, and Fate of PAHs in Lac Saint Louis, Quebec. Chemosphere. (Accepted June 1999)

    Cousins, I.T., Mackay, D. 2000. Correlating the Physical Chemical Properties of Phthalate Esters using the "Three Solubilities Approach". Chemosphere. (Accepted October 1999)

    Woodfine D.G., Seth R., Mackay D., Havas M. 2000. Simulating the Response of Metal Contaminated Lakes to Reductions in Atmospheric Loading Using a Modified QWASI Model. Chemosphere. (Accepted November 1999.)

    Mackay, D., Webster, E., Beyer, A., Matthies, M., Wania, F. "Defining the Bioaccumulation, Persistence, and Transport Attributes of Priority Chemicals" In American Chemical Society Symposium Series on Persistent Organic Pollutants. R. Lipnick, Ed. (In press.)



2. Évaluation systématique des substances éstrogéniques.

    Zacharewski, T.R., McCallum, G.P., Stegeman, J.J. and Bend, J.R. (1996) Hepatic cytochrome P450 1A as a biomarker for hydrocarbon and oxidant pollutants in fish: relevance of identification of specific mechanism(s) of induction and potential effects on homeostasis. In Environmental Toxicology and Risk Assessment: Transboundary Issues in Pollution-Air, Surface and Groundwater (T. W. La Point, F. T. Price, & E. E. Little, Eds.), American Society for Testing and Materials, Philadelphia. p. l65 187.

    Safe, S. and Zacharewski, T. (1997) Organochlorine exposure and breast cancer. In Etiology of Breast Cancer. Progress in Clinical and Biological Research, Vol 396 (C.M. Aldaz, M.N. Gould, J. McLachlan, T.F. Slaga, Eds.). p. 133-146.

    McCallum, C,.P. and Zacharewski, T. (1997) Molecular Toxicology: Applications of recombinant DNA technology. In Encyclopedia of Toxicology (P. Wexler, Ed). Vol. 2, p 335-342.

    Zacharewski, T. and Safe, S. (1997) Antiestrogenic activity of TCDD and related compounds. In Modulation of Endocrine Systems by Xenobiotics (K. Korach, Ed.). p 431- 448.

    Van Der Kraak, G., Zacharewski. T., Janz, D. and Sanders, B. (1998) Comparative endocrinology and mechanisms of endocrine modulation in fish and wildlife. In Principle and Processes for Evaluating Endocrine Disruption in Wildlife (R.J. Kendall, R.L. Dickerson, W.A. Suk, and J.P. Giesy, Eds.). p. 97-119.

    Clemons, J.H. and Zacharewski, T. (1997) Reporter genes in toxicology. In Molecular Biology Approaches to Toxicology (A. Puga and K.B. Wallace, Eds.). In press.

    Zacharewski, T., Berhane, K., Cillesby, B. and Burnison, B.K. (1995) Evidence for the presence of estrogen receptor and Ah receptor ligands in pulp and paper mill black liquor. Environmental Science and Technology, 29, 2140-2146.

    Ruh, M.F., Zacharewski, T., Connor, K., Howell, J., Chen, 1. and Safe, S. (1995) Naringenin: a weakly estrogenic bioflavonoid which exhibits antiestrogenic activity. Biochemical Pharmacology, 50, 1485-1493.

    Connor, K., Howell, J., Chen, I., Liu, H., Berhane, K., Sciarretta, C., Safe, S. and Zacharewski, T. (1996) Failure of chloro-S-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro. Fundamental and Applied Toxicology, 30, 93-101.

    Moore, M., Mustain, M., DaWel, K., Chen, I., Safe, S., Zacharewski, T., Gillesby, B., Joyeux, A. and Balaguer, P. (1997) Antiestrogenic activity of hydroxylated polychlorinated biphenyl congeners identified in human serum. Toxicology and Applied Pharmacology, 142, 160-168, 1997.

    Zacharewski, T. (1997) In vitro bioassays for assessing estrogenic substances. Environmental Science and Technology, 31, 613-623.

    Gillesby, B., Stanostefano, M., Wu, Z. F., Safe, S., and Zacharewtiki, T. (1997) Identification of an inhibitory dioxin-like response elernent (IDRE) required for TCDD- mediated suppression of pS2 expression. Biochemistry, 36, 6080-6089.

    Connor, K., Rarnarnoorthy, K., Moore, M., Mustain, M., Chen, I., Safe, S. Zacharewski, T., Gillesby, B., Joyeux, A. and Balaguer, P. (1997) Hydroxylated polychlorinated biphenyls (PCBS) as estrogens and antiestrogens: structure-activity relationships. Toxicology and Applied Pharmacology, 145,111 123.

    Meek, M.D., Clemons, J.H., Wu, Z.F. and Zacharewski, T. (1997) Examination of the estrogenic activities of eight coriimercial phthalate esters. Fundamental and Applied Toxicology. Submitted

    Fielden, M.R., Chen, I., Chittim, B., Safe, S. and Zacharewski, T. Examination of the estrogenicity of 2,4,6,2',6'-pentacl-dorobiphenyl (PCB104) and its hydroxylated 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB104) and chlorinated, 2,4,6,2',4',6'- hexachlorobiphenyl (PCB155) drivatives. Environmental Health Perspectives. In press

    Gillesby, B.E. and Zacharewski, T. (1998) Endocrine disrupters: mechanisms of action and strategies for identification and assessment. Environmental Toxicology and Chemistry. 17, 3-14.

    Berhane, K. and Zacharewski, T. Bacterial expression of the aryl hydrocarbon receptor (AhR) and its dimerization partner, the aryl hydrocarbon receptor nuclear translocator protein (ARNT). Partially purified A-hR and ARNT are sufficient for binding to a dioxin response element in vitro. In preparation

    Clemons, J.H., Marvin, C.R., Wu, Z.F., McCarry, B.E., Legzdins, A.E., Bryant, D.W. and Zacharewski, T.R. (1998). Identification of estrogen- and dioxin-like activities in urban air particulate material using recombinant receptor/reporter gene bioassays. Environmental Science and Technology, 32, 1853-1860

    Desaulniers, D., Leingartner, K., Zacharewski, T. and Foster, W.G. Optimization of an MCF7-E3 cell proliferation assay and effects of environmental pollutants and industrial chemicals. Toxicology In vitro. In press.

    Balaguer, P., Joyeux, A. M., Denison, M.S., Vincent, R., Cillesby, B. and Zacharewski, T. (1996) Assessing the estrogenic and dioxin-like activities of chemicals and complex mixtures using in vitro recombinant receptor/reporter gene assays. Canadian Journal of Physiology and Pharmacology, 74, 216-222.

    Zacharewski, T. (1997) Endocrine disruption: Strategies for identification and assessment. SGOMSEC 13 - Altemative Toxicological Testing Methods. Environmental Health Perspectives, in press

    Tillit, D., Kramer, V., Purdy, R. and Zacharewski, T. (1997) In vitro screening methods for endocrine disruptors in wildlife. in preparation.

    Zacharewski, T., Campbell P.M., Routledge, E., Cooper, R., Huet, M.-C., Kirne, D. and Wenzel, A. (1997) Current approaches for the use of in vitro tests in identifying the hazards of endocrine modulating chemicals to wildlife. In SETAC-Europe/OECD/EC Expert Workshop on Endocrine Modulators and Wildlife: Assessment and testing (EMWAT) (L. Tattersfield, P. Matthiessen, P. Campbell, N, Grandy, R. Lange, Eds.), SETAC Europe Publication, Brussels. p. 41-58.

    Gray, L.E., Kelce, W.R., Wiese, T., Tyl, R., Gaido, K., Cook, J., Klinefelter, G., Desaulniers, D., Wilson, E., Zacharewski, T., Waller, C., Foster, P., Laskey, J., Reel, J., Giesy, J., Breslin, W., Cooper, R., Di Giulio, R., Welshons, W., Miller, R., Safe, S., McLachlan, J., McMaster, S., Colborn, T. (1997) Endocrine Screening Methods Workshop Report: Detection of Estrogenic and Androgenic Hormonal and Antihormonal Activity for Chemicals that act via Receptor or Steroidogenic Enzyme Mechanisms. Reproductive Toxicology, 11, 719-750.


3. Toxicologie du système de reproduction et du système endocrinien chez le poisson.

Hewitt, L.M., Scott, I.M., Munkittrick, K.R., Van Der Kraak, G.J., Solomon, K.R., and Servos, M.R., 1996. Development of TIEs for complex mixtures using physiological responses in fish. In: Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment Fifth Volume. ASTM STP 1306. (D.A. Bengston and D.S. Henshel, eds.). American Society for Testing and Materials, Philadelphia, pp. 37-52.

Hewitt, L.M., L. Tremblay, G.J. Van der Kraak, K.R. Solomon and M.R. Servos, 1998. Identification of the lampricide 3-trifluoromethyl-4-nitrophenol as an agonist for the rainbow trout estrogen receptor. Environ. Toxicol. Chem. 17:425-432.

Janz, D.M. and G. Van Der Kraak, 1997. Suppression of apoptosis by gonadotropin, 17B-estradiol, and epidermal growth factor in rainbow trout preovulatory ovarian follicles. Gen. comp. Endocrinol. 105:186-193.

Janz, D.M., M.E. McMaster, K.R. Munkittrick, and G. Van Der Kraak, 1997. Elevated ovarian follicular apoptosis and heat shock protein-70 expression in white sucker exposed to bleached kraft pulp mill effluent. Toxicol. Appl. Pharmacol. 147:391-398.

Tremblay, L. and G. Van der Kraak, 1998. Use of a series of homologous in vitro and in vivo assays to evaluate the endocrine modulating actions of beta-sitosterol in rainbow trout. Aquat. Toxicol. 43:149-162.

Tremblay, L. and G. Van der Kraak, 1999. Comparision between the effects of the phytosterol B-sitosterol and pulp and paper mill effluents on sexually immature rainbow trout. Environ. Toxicol. Chem., in press.


4. Évaluation du risque environnemental associé aux hydrocarbures aromatiques halogénés. (95-02)

Morrison, H.A., D.M. Whittle, C.D. Metcalfe and A.J. Niimi, 1999. Verification and use of a food web bioaccumulation model for the prediction of PCB, dioxin and furan congener concentrations in Lake Ontario biota. Can. J. Fish. Aquat. Sci. 56 (In press).

Morrison, H.A., C.D. Metcalfe, D. Mackay, A.J. Niimi and D.M. Whittle. Assessing the risk to Lake Ontario anglers consuming sport fish contaminated with halogenated aromatic hydrocarbons. Environ. Health Persp. (Accepted).


5. Métabolites des BPC dans le plasma et le lait humains. (95-04)

Sandau C.D., Norstrom R.J. Comparison of methylation methods for the determination of hydroxy-PCBs and preliminary results for polar bear blood plasma. Organohalogen Compounds 29:412-417 (1996).

Sandau C.D., Ayotte, P., Dewailly, E., Bergman, A., Klasson-Wehler, E., Norstrom R.J. Analysis of hydroxylated metabolites of PCBs (OH-PCBs) in whole blood from Canadian Inuit. Organohalogen Compounds 38:29-32 (1998)

C.D. Sandau, R.J. Norstrom. Analysis of hydroxylated metabolites of PCBs (OH-PCBs) in polar bear plasma and human whole blood. EnviroAnalysis'98, Proceedings of the second biennial international conference on chemical measurement and monitoring of the environment. 405-410 (1998)

Sandau, C.D., P. Ayotte, E. Dewailly, J. Duffe and R.J. Norstrom. 2000. Analysis of hydroxylated metabolites of PCBs (OH-PCBs) and other chlorinated phenolic compounds in whole blood from Canadian Inuit. Environ. Health Persp. (in press)

Sandau, C.D., I.T.M. Meerts, R.J. Letcher, A.J. McAlees, B. Chittim, A. Brouwer and R.J. Norstrom. 2000. Identification of 4-hydroxy-heptachlorostyrene in polar bear plasma and its binding affinity to transthyretin: a metabolite of octachlorostyrene? Submitted to ES&T

Sandau, C.D., P. Ayotte, E. Dewailly, J. Duffe, R.J. Norstrom. PCP and hydroxylated metabolites of PCBs in umbilical cord plasma from three different regions of Quebec - Nunavik, Gulf of the St. Lawrence and Quebec City. (In prep.)


6. Synthèse et toxicologie aquatique de chloroalcanes individuels de différentes origines (95-05)

Fisk, A.T., G.T. Tomy, and D.C.G. Muir. 1999. The toxicity of C10, C11-, C12- and C14- polychlorinated alkanes to Japanese medaka (Oryzias latipes) embryos. Environ. Toxicol. Chem. 18(12): In press.

Cooley, M., Fisk, A.T., Wiens, S., Tomy, G.T. and D.C.G. Muir. 2000. Examination of the behavior and the liver, kidney and thyroid histology of juvenile rainbow trout (Oncorhynchus mykiss) exposed to high dietary concentrations of C10-, C11-, C12- and C14-polychlorinated n-alkanes. In preparation. Aquatic Toxiol.

Fisk, A.T., Tomy, G.T., Cymbalisty, C.D. and D.C.G. Muir. 1999. Dietary accumulation, depuration and biodegradation of short (C10), medium (C14) and long (C18) carbon chain polychlorinated alkanes by juvenile rainbow trout (Oncorhynchus mykiss): Relationships with carbon chain length and chlorine content. In preparation. Environ. Toxicol. Chem. Submitted June,1999.


7. Tératogénicité relative des congénères du toxaphène prévalants dans l'environnement.

Stalzer, A. Chan, H.M. (1999) The relative estrogenic activity of technical toxaphene mixture and two individual congeners. Toxicology. In press.

Chan, H.M., Zhu, J., Yeboah, F. (1998) Determination of toxaphene in biological samples using high resolution GC coupled with ion trap MS/MS. Chemosphere, 36:2135-2148.

Calciu, C., Chan, H.M. Kubow, S. (1997) Toxaphene congeners differ from toxaphene mixtures in their dysmorphogenic effects on cultured rat embryos. Toxicology, 153-162.


8. Étude de l'occurrence, de la distribution et de l'origine biogénétique des composés chlorés organiques, y compris les dioxines et les furanes polychlorés, dans les tourbières.

Silk, P.J., G.C. Lonergan, T.L. Arsenault, and C.D. Boyle, 1997. Evidence of natural organochlorine formation in peat bogs. Chemosphere 35:2865-2880.


9. Inventaire canadien des émissions de produits chlorés.

Johnson, N.D., M.T. Scholtz, and T. Shapiro, 1997. Organochlorine Sources: A Review. Canadian Global Emissions Interpretation Centre Final Report, ORTECH Corp., and Environment Canada, Mississauga, ON


10. Chaire de recherche sur la divulgation des risques et les politiques publiques, University of Calgary.

11. Évaluation des risques liés aux composés chlorés au niveau des populations par l'utilisation de méthodes de modélisation des individus.

Power, M., 1977. Assessing the effects of environmental stressors on fish populations. Aquatic toxicology 39:151-169.

Power, M., M.J. Attrill, and R.M. Thomas, 1999. Trends in agricultural pesticide (atrazine, lindane, simazine) concentrations in the Thames Estuary. Environ. Pollut. 104:31-39.]

Power, M. and L.S. McCarty, in press. sing Risk-cost Trade-offs in Environmental Risk Management Decision-making. Environ. Sci. Policy.


12. Évaluation probabiliste des risques pour les nouveau-nés associés à la consommation de lait maternel contenant des organochlorés.

Hoover, S.M., 1999. Exposure to Persistent Organochlorines in Canadian Breast Milk: A probabilistic Assessment. Risk Analysis, 19(4): 527-545.


13. L'environnement et ses impacts sur la santé des enfants - Une incitation à agir.

    CICH, 1997. A National Symposium on Environmental Contaminats and the Implications for Child Health. Proceedings of a Conference Held in Ottawa ON, May 25-27, 1997. Distributed on diskette.

    CICH, 1997. Environmental Hazards: Protecting Children. Information sheets for pesticides, hormone disruptors, breastfeeding, asthma, childhood cancers, reproductive abnormalities, prenatal exposure, neurodevelopmental effects, and respiratory health. 36 pages.

    Harmsen, E., D. Avard, G. Chance, K. Underwood, 1999. Environmental Contaminants and the Implications for Child Health: Literature Review (Second Draft). Canadian Institute of Child Health, Ottawa ON, 99 pg.


14. Sources et flux de certains composés organochlorés volatiles entre l'atmosphère et l'océan. (95-18)

    Moore, R. M., 2000. The solubility of a suite of low molecular weight organochlorine compounds in seawater and implications for estimating the marine source of methyl chloride to the atmosphere. Chemosphere: Global Change Science 2, 95-99.

    Murphy, C.D., R.M. Moore, and R.L. White, 2000. An isotopic-labeling method for determining production of volatile organohalogens by marine microalgae. Limnol. Oceanogr., January.

    Scarratt, M.G. and R. M. Moore Production of chlorinated hydrocarbons by the red microalga, Porphyridium purpureum. Limnol. Oceanogr. 44, 703-707, 1999.

    Khalil, M.A.K., R.M. Moore, D.B. Harper, J.M. Lobert, V. Koropalov and W.T. Sturges, and W. C. Keene. Natural emissions of chlorine-containing gases: The Reactive Chlorine Emissions Inventory. J. Geophys. Res. (Atmos), 104, 8,333-8,346, 1999.

    Keene, W. C., M. A. K. Khalil, D. J. Erickson, A. McCulloch, T. E. Graedel, J. M. Lobert, M. L. Aucott, S.-L. Gong, D. B. Harper, G. Kleiman, P. Midgley, R. M. Moore, C. Seuzaret, W. T. Sturges, C. M. Benkovitz, V. Koropalov, L. A. Barrie, and Y.-F. Li, Composite global emissions of reactive chlorine from anthropogenic and natural sources: The Reactive Chlorine Emissions Inventory. J. Geophys. Res. (Atmos). 104, 8,429-8,440,
    1999.

    Murphy, C.D., R.M. Moore, and R.L. White, Peroxidases from Marine Microalgae. J. Appl. Phycol., submitted Sept. 24, 1999.

    Scarratt, M.G. and R.M. Moore, 1998. Production of methyl chloride and methyl bromide in laboratory cultures of marine phytoplankton II. Marine Chemistry, 59, 311-320.


15. Méthode de vérification environnementale pour les gestionnaires de l'industrie du chlore.

Willis, R.D.A., 1997. Development of An Environmental Issue Audit Methodology for Chlorine Industry Managers. M.E.S. Thesis, Dalhousie University, Halifax, Nova Scotia, 481 pg.


16. Évaluation de l'impact de l'altitude et de la température sur les retombées atmosphériques de polluants persistants en Alberta et en Colombie-Britannique. (96-02)

Blais, J.M., D.W. Schindler, D.C.G. Muir, L.E. Kimpe, D.B. Donald, B. Rosenberg. 1998. Accumulation of persistent organochlorine compounds in mountains of western Canada. Nature 395: 585-588.

Blais, J.M. 1998. Altitudinal trends of persistent organic pollutant deposition. In K.A. Kidd, R.E. Hecky (Eds) Interrelationships Among Climatic Variation, Climate Change and Persistent Organic Pollutant Cycling in the Americas. NWRI Contribution No. 98-128: 54-56.

Blais, J.M., D.W. Scindler, D.C.G. Muir, S. Backus, M. Comba. In Preparation. Toxaphene deposition and cold-condenation in the Canadian Rocky Mountains.


17. Élaboration d'une vision synoptique des tendances à long terme des teneurs en organochlorés dans l'écosystème des Grands Lacs.

    Cole, J.G., Mackay, D., Jones, K.C., Alcock, R.E. 1999. Interpreting, Correlating, and Prediciting the Multimedia Concentrations of PCDD/Fs in the United Kingdom. Environ. Sci. Technol. 33: 399-405.

    Webster, E., Mackay, D., Qiang, K. 1999. Equilibrium Lipid Partitioning Concentrations as a Multi-Media Synoptic Indicator of Contaminant Levels and Trends in Aquatic Ecosystems. J. Great Lakes Res. 25: 318-329.

    Bentzen, E., Mackay, D., Hickie, B.E., Lean, D.R.S. 1999. Temporal trends of persistent organic pollutants in Lake Ontario compared between species and between data sources. Environmental Reviews. (Accepted June 1999)


22. Rôle du métabolisme fongique dans la genèse des organochlorés dans la tourbe : mécanismes de formation et devenir dans l'environnement.

Silk, P.J., Lonergan, G., and Macaulay, J. Aspects of the Organic Chemistry of Peat: Chlorocompounds and Fungal Metabolism. Submitted to Chemosphere, Sept., 1999.

Silk, P.J., Aubry, C., Lonergan, G., and Macaulay, J. Aspects of Chlorometabolite Production by the Ecologically Important White Rot Fungus, Bjerkandera adusta. Submitted to J. Chemical Ecology, Sept., 1999


24. Utilisation de modèles multimédias dans le dépistage de polluants organiques rémanents (POR).

Beyer, A., Mackay, D., Matthies, M., Wania, F., Webster, E. Assessing the Long-Range Transport Potential of Persistent Organic Pollutants. Submitted to Environ. Sci. Technol.

Mackay, D., Webster, E., Beyer, A., Matthies, M., Wania, F. Defining the Partitioning Bioaccumulation, Persistence, and Transport Attributes of Priority Chemicals. In: Lipnick, R.L. et al. (eds.) Proceedings of the Symposium on Persistent, Bioaccumulative, Toxic Substances held at the 217th ACS national Meeting, Anaheim, CA, March 21-25, 1999.

 


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